Why it matters
Drug-drug interactions are a leading preventable cause of serious adverse events. A significant share of medication-related hospitalisations could be avoided through systematic interaction checks at prescription and dispensing.
Highest-risk combinations
- Oral anticoagulants (VKAs, DOACs) with NSAIDs, certain antibiotics (macrolides), azole antifungals.
- SSRI antidepressants with triptans or tramadol (serotonin syndrome risk).
- Statins with some antibiotics or grapefruit juice (rhabdomyolysis risk).
- Paracetamol at maximum dose in patients on warfarin (INR potentiation).
Recommended habits
- Keep a complete and up-to-date list of every treatment, including OTC, herbal and supplements.
- Ask your pharmacist for an interaction check with every new prescription.
- Report any unusual effect via the official pharmacovigilance portal.
How CureIQ can help
You can ask CureIQ for free: “Are my medications compatible with each other?” — the assistant cross-checks your treatments against official databases (ANSM, HAS, WHO) and returns a clear, sourced answer.